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Symbol
Name
ID
Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
MGI:107172
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal blood vessel morphology
abnormal angiogenesis
abnormal vascular endothelial cell development
absent vitelline blood vessels
disorganized yolk sac vascular plexus
abnormal myocardial fiber morphology
abnormal heart development
abnormal heart morphology
increased heart left ventricle size
increased heart right ventricle size
thin ventricular wall
distended pericardium
cardiac interstitial fibrosis
dilated cardiomyopathy
decreased cardiac muscle contractility
abnormal heart echocardiography feature
increased cardiomyocyte apoptosis
congestive heart failure
Availability Mouse Genotype
Ppp3r1tm1.1Jhon/Ppp3r1tm1.1Jhon
Ppp3r1tm1Grc/Ppp3r1tm1Grc
Ppp3r1tm2.1Grc/Ppp3r1tm2.1Grc
Ppp3r1tm2Grc/Ppp3r1tm2Grc
Tg(GATA5-cre)1Krc/0  (conditional)
*
Ppp3r1tm2Grc/Ppp3r1tm2Grc
Tg(Tagln-cre)1Her/0  (conditional)
*
Ppp3r1tm2Grc/Ppp3r1tm2Grc
Tg(Tek-cre)1Ywa/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory